Mario Wiesenfeldt was born in Ludwigshafen am Rhein and studied chemistry at the Ruprecht Karls-Universität Heidelberg, where he worked with Prof. Lutz Gade. Following an exchange semester at the University of York, Mario conducted the research towards his master thesis in the group of Prof. Brian Stoltz at the California Institute of Technology. In 2015, Mario joined the group of Prof. Frank Glorius at the WWU Münster to develop selective arene hydrogenation reactions before moving to Princeton in 2019 to conduct a postdoctoral stay in the group of Prof. David MacMillan. In the MacMillan group, he developed new syntheses of bioisosteres and functionalizations thereof via photoredox catalysis. In October 2021, Mario started his independent career at the RU Bochum and at the MPI für Kohlenforschung.